Biological Sciences 321HG - Conference Course: 'Molecular Genetics and Human Genetic Disorders'

Mendel's principles of genetic inheritance underpin all the inheritance patterns that we observe and the traits they govern. However, in nature, not all is as it first appears. Many traits seem to diverge from Mendelian genetics until we understand those inheritance patterns more deeply. In this course, we will explore the depths of genetic inheritance by first understanding the mechanisms of these seeming "exceptions of Mendelian inheritance". We will then understand how the molecule of DNA behaves in the nucleus to allow for gene expression and how we study DNA in the lab. Finally, we will discuss human genetic disorders that occur because of deviations in gene expression or DNA behavior but are rooted in Mendelian genetic principles. The capstone experience of the course is a student-group project exploring experimental approaches for diagnosing or treating a human genetic disorder.

Prereq: BIOL-200 and BIOL-210, or BIOL-220 or BIOL-230.